A Simple Key For cees dekker Unveiled
A Simple Key For cees dekker Unveiled
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Working with solitary-molecule optical and AFM imaging and force-spectroscopy procedures, we search for to unravel the mechanistic facets of the structure and dynamics of chromosomes. Our study pursuits include things like:
You often become involved in discussions about science and religion. You might have also created quite a few textbooks on the topic. Don’t you imagine that sooner or later We're going to know every little thing Which God’s part will be in excess of?
Again in 1991, Sumio Iijima in the NEC Corporation had documented the synthesis of carbon nanotubes. Band framework calculations proposed that these nanotubes could show metallic band conduction. This may be a big edge about the conducting polymers we experienced explored, which ended up, in truth, disordered semiconductors presenting basically variable-array hopping conductivity.
Given that 2000, Dekker has shifted the leading focus of his operate to biophysics exactly where he reports the Attributes of single biomolecules and cells using the instruments of nanotechnology. This alteration of area was driven by his fascination for that extraordinary operating of Organic molecular buildings, as well as through the very long-time period perspective that a lot of exciting discoveries is often envisioned in this area.[5] Existing traces of exploration in his biophysics team are from the parts of:[six]
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Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of an individual wire bridging two electrodes
‘In the beginning we checked out Organic techniques that has a physical check out and acted on The premise of the resources we understood. It took a number of years before we started out Performing more on the big biological troubles. I then began to connect with it nanobiology, a term that did not exist at time.
Nanopores represent an elegant and flexible Device to measure solitary molecules. We analysis novel detection modes with sound-condition nanopores along with different strategies to measure proteins with nanopores. Tasks encompass the following:
‘You should not just think about the concerns of tomorrow, but additionally think about the queries on the day right after tomorrow’
one). The present–voltage curves confirmed considerable modulations with gate voltage, even at home temperature, which was per band bending inside a ~0.six eV bandgap semiconducting nanotube. These data also confirmed which the conductance may be modulated by 6 orders of magnitude by modifying the gate voltage. The effects of this get the job done — a area-temperature transistor made from an individual carbon nanotube molecule — were being printed in Mother nature in Might 1998.
An integrated microfluidic platform for quantifying drug permeation throughout biomimetic vesicle membranes
‘That concerns the synthetic ceesdekker mobile, as A part of the Dutch BaSyC initiative. Craig Venter appeared leading-down in All those days and recognized about 5 hundred genes which are minimally expected for a working mobile. We wish to search base-up: how can we move from a couple molecules to a complete biological process?
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of an individual wire bridging two electrodes
Supercoiling-dependent DNA binding: quantitative modeling and purposes to bulk and solitary-molecule experiments